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  • Unlocking the secrets of our compulsions :: U-M Psychiatry and Depression Center Newsroom
    the rat s brain was related to the lever s ability to accurately predict the appearance of food or whether it made the lever desirable in its own right The answer the researchers found is that it depends on what kind of rat you are Think of it this way Flagel says Some people will see a sign for an ice cream shop and for them it s simply that an indicator that ice cream is available nearby But other people will have a stronger reaction to the sign the tantalizing association between the sign and ice cream is so powerful they can already taste the treat and often hurry to buy some The researchers studied rats that had been selectively bred for certain behavioral traits including different proclivities for addictive drugs Rats in the drug prone group tended to focus their attention on the lever The other group cared a lot more about the place where the food actually appeared Still if the rats brains saw the lever merely as a signal that accurately predicted the arrival of the food the dopamine reward for both groups should be the same However if the dopamine reward was tied to the strength of the rats desire for the lever itself one would expect a different pattern for each of the two groups And that s exactly what happened U M s collaborators at the University of Washington used a technique called fast scan cyclic voltammetry to measure the dopamine responses in the rats brains as they shifted over mere fractions of a second Their analysis showed that the drug prone rats got a jolt of happiness just from the lever while the food oriented rats did not And their desire for the lever continued even when the food reward was removed The study additionally measured the rats ability to learn when dopamine was blocked and repeated the experiments with rats that had not been selectively bred Flagel co lead author Jeremy J Clark Ph D of UW and their colleagues hope the animal model will help scientists figure out why some people are more strongly motivated by environmental cues and therefore at increased risk for compulsive behavior or among addicts relapse We have been interested in understanding how differences in temperament control our day to day behavior how they determine the types of pathologies we express says Huda Akil Ph D co director of MBNI a professor of neuroscience at U M and co senior author of the study This study helps us understand how in some situations dopamine amplifies messages in the world around us playing a role in controlling behaviors Meanwhile Paul E M Phillips Ph D Akil s counterpart at UW emphasized the collaboration Collectively the contributions of our groups amounted to something much more important than the sum of the components Funding National Institutes of Health Office of Naval Research Citation 10 1038 nature09588 Additional U M Authors Terry E Robinson Ph D Leah Mayo B S

    Original URL path: http://ummentalhealth.info/2010/12/09/unlocking-the-secrets-of-our-compulsions/ (2016-05-02)
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  • New tool aims to improve measurement of primary care depression outcomes :: U-M Psychiatry and Depression Center Newsroom
    Diagnostic and Statistical Manual of Mental Disorders DSM IV doesn t necessarily correspond to a patient s own sense of recovery Nease explains For example a patient could meet all the criteria for full remission but still not feel that he had recovered The U M questionnaire which is called Remission Evaluation and Mood Inventory Tool or REMIT is intended to add the patient s subjective sense of recovery into the equation Rather than a replacement for current tools and measurements REMIT is intended to compliment them say Nease who is currently an adjunct professor at U M The researchers used the REMIT tool alongside the current gold standard for monitoring people with depression the Patient Health Questionnaire PHQ Nease explains The data showed that by adding in the REMIT questions about one third of patients with mild depression were not in remission as their PHQ score would indicate Additionally about one third of moderately depressed patients were doing better than their PHQ scores alone would denote Using just the PHQ score across our study population we saw about 60 percent accuracy in reflecting a patient s remission compared to the patient s sense of his or her own recovery Nease says If you add in the REMIT questions we get above 70 percent This can give doctors new insights when making treatment choices such as changing a patient s medication or dosage The current research looked at a single snapshot in time for nearly 1 000 patients The next step will be to track patients scores over time Unlike other tools that require a company s permission to use the REMIT tool is available to any doctor who wants to use it Nease says Additional Authors James E Aikens Ph D Michael S Klinkman M S M D Ananda

    Original URL path: http://ummentalhealth.info/2011/05/26/new-tool-aims-to-improve-measurement-of-primary-care-depression-outcomes/ (2016-05-02)
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  • UMHS Press Release :: U-M Psychiatry and Depression Center Newsroom
    U M is one of 10 sites in the Bipolar Trials Network that will participate in the national study which is supported by a federal Read this story Resurrecting the so called depression gene January 3 2011 ANN ARBOR Mich University of Michigan Health System researchers have found new evidence that our genes help determine our susceptibility to depression Their findings published online today in the Archives of General Psychiatry challenge a 2009 study that called the genetic link into question Read this story Unlocking the secrets of our compulsions December 9 2010 New findings on how rats make choices may provide insights into addiction and impulse driven behavior ANN ARBOR Mich Researchers have shed new light on dopamine s role in the brain s reward system which could provide insight into impulse control problems associated with addiction and a number Read this story Researchers track the impacts of depression during pregnancy December 9 2010 Babies born to depressed moms have higher levels of stress hormones decreased muscle tone U M study finds ANN ARBOR Mich The cocktail of hormones cascading through depressed mothers bodies may play an important role in the development of their unborn children s brains A higher level of Read this story U M study pep talks to teens in the ER reduce violence alcohol misuse August 3 2010 Teens in the ER got the message about avoiding fights and drinking study shows Ann Arbor Mich A brief motivational talk in the emergency room reduced by half the chances that teenagers would experience peer violence or problems due to drinking according to a study published Aug 4 in a theme Read this story Individuals confess alcohol abuse to clergy U M study finds July 20 2010 Majority of those who used services from clergy also used

    Original URL path: http://ummentalhealth.info/category/pressrelease/page/8/ (2016-05-02)
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  • Linas Bieliauskas wins the 2010 Russell J. Bent Award :: U-M Psychiatry and Depression Center Newsroom
    award reflects the hard work and dedication Dr Bieliauskas has shown the American Board of Professional Psychology Dr Bieliauskas is a clinical specialist in neuropsychology closed head injuries dementing disorders and Parkinson s disease His research interests include cognitive and personality changes with normal and abnormal aging psychometric indicators of cognitive disorders depression and dementia and neuropsychological predictors of critical life tasks Recent Entries Dr Monica Starkman professor emeritus publishes novel based on career in psychiatry Who gets hooked on drugs who stays clean Study in rats finds genetic markers that influence addiction UMHS community mourns death of Kenneth Silk M D Taking the fight against risky pain pill use to the ER Study shows promise Fashion design meets U M research in wearable human stem cell images Featured Video Recent Posts Dr Monica Starkman professor emeritus publishes novel based on career in psychiatry Who gets hooked on drugs who stays clean Study in rats finds genetic markers that influence addiction UMHS community mourns death of Kenneth Silk M D Taking the fight against risky pain pill use to the ER Study shows promise Fashion design meets U M research in wearable human stem cell images Twitter Tweets Categories Featured

    Original URL path: http://ummentalhealth.info/2010/06/15/linas-bieliauskas-wins-the-2010-russell-j-bent-award/ (2016-05-02)
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  • Judith Coucouvanis Wins Award for New Book :: U-M Psychiatry and Depression Center Newsroom
    Resources Competition By using a humorous approach in guiding parents through their child s potty training journey the book has helped produce wonderful results for children with autism and other related disorders The publication also offers insight from parents educators and child care providers who have followed the strategies presented in the book For more information on the Autism Spectrum Disorders Clinic in the Department of Psychiatry please visit http www psych med umich edu care child asd asp Recent Entries Dr Monica Starkman professor emeritus publishes novel based on career in psychiatry Who gets hooked on drugs who stays clean Study in rats finds genetic markers that influence addiction UMHS community mourns death of Kenneth Silk M D Taking the fight against risky pain pill use to the ER Study shows promise Fashion design meets U M research in wearable human stem cell images Featured Video Recent Posts Dr Monica Starkman professor emeritus publishes novel based on career in psychiatry Who gets hooked on drugs who stays clean Study in rats finds genetic markers that influence addiction UMHS community mourns death of Kenneth Silk M D Taking the fight against risky pain pill use to the ER Study shows

    Original URL path: http://ummentalhealth.info/2010/04/19/judith-coucouvanis-wins-award-for-new-book/ (2016-05-02)
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  • U-M Joins Dartmouth, Cornell and University of Washington in Receiving NIMH Funding for Training Grant :: U-M Psychiatry and Depression Center Newsroom
    years It includes the following researchers and their respective Universities Stephen Bartels Dartmouth Marty Bruce Cornell and Jurgen Unutzer University of Washington Researchers from the University of Michigan were invited to join this collaborative training program in the competing renewal so now there will be a total of four sites Special thanks to the following individuals for their willingness and commitment to participate in the grant application Helen Kales Alan Mellow John McCarthy Amy Kilbourne Scott Kim Kris Barry Kara Zivin Psychiatry Ken Langa and John Piette Internal Medicine Myra Kim Biostatistics Jane Banaszak Holl and Woody Neighbors School of Public Health and Lou Burgio School of Social Work Additional thanks to Janet Kavanagh who was instrumental in pulling together content for the submission Due to the University of Michigan being a new site candidates have not been established for the training grant this year If anyone has a potential candidate MD or PhD please let Dr Blow know so he can begin having dialogues with potential candidates for next year Dr Blow is a Professor and Director of Mental Health Services Outcomes Translation Section for the Department of Psychiatry and the Director National Serious Mental Illness Treatment Research Evaluation Center for the Department of Veterans Affairs Recent Entries Dr Monica Starkman professor emeritus publishes novel based on career in psychiatry Who gets hooked on drugs who stays clean Study in rats finds genetic markers that influence addiction UMHS community mourns death of Kenneth Silk M D Taking the fight against risky pain pill use to the ER Study shows promise Fashion design meets U M research in wearable human stem cell images Featured Video Recent Posts Dr Monica Starkman professor emeritus publishes novel based on career in psychiatry Who gets hooked on drugs who stays clean Study in rats

    Original URL path: http://ummentalhealth.info/2010/03/18/u-m-joins-dartmouth-cornell-and-university-of-washington-in-receiving-nimh-funding-for-training-grant/ (2016-05-02)
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  • James Cranford Wins MICHR Award Funding :: U-M Psychiatry and Depression Center Newsroom
    McCabe U M Institute for Research on Women and Gender Dr Howard Tennen University of Connecticut Health Center Dr Masha Ivanova University of Vermont and Dr Robert A Zucker U M Addiction Research Center The MICHR Pilot Grant Program considers proposals from basic clinical and social scientists for bench to bedside and bedside to practice translational research The goal is to promote development of novel solutions that will ultimately improve patient and community health outcomes Recent Entries Dr Monica Starkman professor emeritus publishes novel based on career in psychiatry Who gets hooked on drugs who stays clean Study in rats finds genetic markers that influence addiction UMHS community mourns death of Kenneth Silk M D Taking the fight against risky pain pill use to the ER Study shows promise Fashion design meets U M research in wearable human stem cell images Featured Video Recent Posts Dr Monica Starkman professor emeritus publishes novel based on career in psychiatry Who gets hooked on drugs who stays clean Study in rats finds genetic markers that influence addiction UMHS community mourns death of Kenneth Silk M D Taking the fight against risky pain pill use to the ER Study shows promise Fashion design meets

    Original URL path: http://ummentalhealth.info/2009/11/12/james-cranford-wins-michr-award-funding/ (2016-05-02)
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  • Michelle Riba Recognized as one of America’s Top Doctors :: U-M Psychiatry and Depression Center Newsroom
    president Castle Connolly s goal is to help guide consumers to America s top doctors and top hospitals Castle Connolly s established survey and research process under the direction of an MD involves tens of thousands of top doctors in America and the medical leadership of leading hospitals As a result finding doctors and top hospitals can be a simple and painless process for all Recent Entries Dr Monica Starkman professor emeritus publishes novel based on career in psychiatry Who gets hooked on drugs who stays clean Study in rats finds genetic markers that influence addiction UMHS community mourns death of Kenneth Silk M D Taking the fight against risky pain pill use to the ER Study shows promise Fashion design meets U M research in wearable human stem cell images Featured Video Recent Posts Dr Monica Starkman professor emeritus publishes novel based on career in psychiatry Who gets hooked on drugs who stays clean Study in rats finds genetic markers that influence addiction UMHS community mourns death of Kenneth Silk M D Taking the fight against risky pain pill use to the ER Study shows promise Fashion design meets U M research in wearable human stem cell images Twitter

    Original URL path: http://ummentalhealth.info/2009/11/12/michelle-riba-recognized-as-one-of-americas-top-doctors/ (2016-05-02)
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