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  • Unconscious conflict linked to anxiety symptoms :: U-M Psychiatry and Depression Center Newsroom
    electrodes record the brain responses to them In a previous experiment Shevrin had demonstrated that time frequency features a type of brain activity showed that patients grouped the unconscious conflict stimuli together only when they were presented subliminally But the conscious symptom related stimuli showed the reverse pattern brain activity was better grouped together when patients viewed those words supraliminally Only when the unconscious conflict words were presented unconsciously could the brain see them as connected Shevrin notes What the analysts put together from the interview session made sense to the brain only unconsciously However the experimental design in this first experiment did not allow for directly comparing the effect of the unconscious conflict stimuli on the conscious symptom stimuli To obtain evidence for that next level the unconscious conflict stimuli were presented immediately prior to the conscious symptom stimuli and a new measurement was made of the brain s own alpha wave frequency at 8 13 cycles per second that had been shown to inhibit various cognitive functions Highly significant correlations suggesting an inhibitory effect were obtained when the amount of alpha generated by the unconscious conflict stimuli were correlated with the amount of alpha associated with the conscious symptom alpha but only when the unconscious conflict stimuli were presented subliminally No results were obtained when control stimuli replaced the symptom words The fact that these findings are a function of inhibition suggests that from a psychoanalytic standpoint that repression might be involved These results create a compelling case that unconscious conflicts cause or contribute to the anxiety symptoms the patient is experiencing says Shevrin who also holds an emeritus position in the Department of Psychology in U M s College of Literature Science and the Arts These findings and the interdisciplinary methods used which draw on psychoanalysis cognitive psychology and neuroscience demonstrate that it is possible to develop an interdisciplinary science drawing upon psychoanalytic theory He notes that a prominent critic of psychoanalysis and Freudian theory Adolf Grunbaum Ph D professor of the philosophy of science at the University of Pittsburgh has expressed satisfaction that the new results when added to previous evidence show that fundamental psychoanalytic concepts can indeed be tested in empirical ways For more than 40 years Shevrin has led a team that has pushed at the boundaries between the disciplines of neuroscience cognitive psychology and psychoanalysis looking for evidence that Freudian concepts such as the unconscious and repression could be documented through physical measures of brain activity His work has explored the territory where neurobiology thoughts emotions and behavior meet In 1968 he published the first report of brain responses to unconscious visual stimuli in Science thus providing strong objective evidence for the existence of the unconscious at a time when most scientists were skeptical of Freud s ideas In that same study he showed that unconscious perceptions are processed in different ways from conscious perceptions a finding consistent with Freud s views on how the unconscious works In recent years exchanges between Grunbaum

    Original URL path: http://ummentalhealth.info/2012/06/18/unconscious-conflict-linked-to-anxiety-symptoms/ (2016-05-02)
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  • Severity of chronic pain and related mood disorders linked to neighborhood status :: U-M Psychiatry and Depression Center Newsroom
    and health management and policy which appears in the current issue of the Journal of Pain Living in a lower socioeconomic neighborhood was associated with increased chronic pain pain related disability and mood disorders like depression and anxiety The study demonstrates that the characteristics of where a patient lives including structural barriers affluence and access to resources such as pain medications play an important role in pain management Read the full press release here http www uofmhealth org news neighborhoods pain Recent Entries Dr Monica Starkman professor emeritus publishes novel based on career in psychiatry Who gets hooked on drugs who stays clean Study in rats finds genetic markers that influence addiction UMHS community mourns death of Kenneth Silk M D Taking the fight against risky pain pill use to the ER Study shows promise Fashion design meets U M research in wearable human stem cell images Featured Video Recent Posts Dr Monica Starkman professor emeritus publishes novel based on career in psychiatry Who gets hooked on drugs who stays clean Study in rats finds genetic markers that influence addiction UMHS community mourns death of Kenneth Silk M D Taking the fight against risky pain pill use to the ER

    Original URL path: http://ummentalhealth.info/2012/03/01/severity-of-chronic-pain-and-related-mood-disorders-linked-to-neighborhood-status/ (2016-05-02)
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  • The Coexistence of Depression and Anxiety :: U-M Psychiatry and Depression Center Newsroom
    professor of psychiatry and social work discussed risk factors for the co occurrence of depression and anxiety and treatment options that have applications for both disorders in Psychology Today Recent Entries Dr Monica Starkman professor emeritus publishes novel based on career in psychiatry Who gets hooked on drugs who stays clean Study in rats finds genetic markers that influence addiction UMHS community mourns death of Kenneth Silk M D Taking the fight against risky pain pill use to the ER Study shows promise Fashion design meets U M research in wearable human stem cell images Featured Video Recent Posts Dr Monica Starkman professor emeritus publishes novel based on career in psychiatry Who gets hooked on drugs who stays clean Study in rats finds genetic markers that influence addiction UMHS community mourns death of Kenneth Silk M D Taking the fight against risky pain pill use to the ER Study shows promise Fashion design meets U M research in wearable human stem cell images Twitter Tweets Categories Featured Honors Awards In Memoriam In the News UMHS Press Release Uncategorized Tags addiction alcohol alcoholism antipsychotics anxiety autism bipolar bipolar disorder bipolar research cancer chronic pain college mental health cortisol DBSA dementia depression

    Original URL path: http://ummentalhealth.info/2011/02/08/the-coexistence-of-depression-and-anxiety/ (2016-05-02)
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  • High anxiety? U-M research looks to brain & genes to improve treatment :: U-M Psychiatry and Depression Center Newsroom
    highlights a new avenue that we need to explore further as we try to develop novel medications while the sertraline study will try to find out if we can tell which patients might or might not respond well and by what mechanism to an already existing medication known to have some efficacy in treating anxiety disorders More information about the new study is available on the U M Engage Web site or via 734 232 0199 or socialphobia umich edu Phan led the cannabis study at the University of Chicago collaborating with Harriet deWit Ph D the director of the Human Behavioral Pharmacology Laboratory in the Department of Psychiatry there Their results are based on brain scans of 16 recreational marijuana users who agreed to undergo functional magnetic resonance imaging or fMRI The researchers chose fMRI because it allows them to see in real time which areas of the brain are most active while a volunteer is performing a certain task for example viewing a picture of a human face that is expressing anger or fear or performing a decision making exercise That same approach will be used in the new sertraline study with two different scans before and after anxiety patients are prescribed the medication The healthy volunteers in the study will also have fMRI scans though they will not receive the drug All study participants must between 18 and 55 years old and those with anxiety disorders must not be taking any other medication that could be affecting the brain in order to qualify to enter the study The cannabis study used THC and a placebo caplet that looked exactly like the THC caplet The researchers found that when the marijuana users received THC their brain s response to threatening faces was less than it was when they received a placebo The difference in response was seen in an area of the brain called the amygdala which is a hub for the brain s ability to process signs of danger or warning and to decide how to respond But there were no differences between THC and placebo in the areas of the brain that process non emotional visual signals or govern body movement suggesting that THC had a specific effect on a specific brain region and on a specific task of processing fear Other researchers have shown this to be a region that s rich in a receptor called CB1 part of the brain s cannabinoid system The human brain produces compounds called endocannabinoids that act on these receptors and are involved in anxiety and fear learning or the learning of which threats to be afraid of But little has been known about the effect of THC an exogenous cannabinoid on the brain s own system For ethical reasons the researchers did not give THC to non marijuana users and the study was small But the findings in the study volunteers suggest that THC and other compounds that act on the CB1 receptors in the amygdala could be

    Original URL path: http://ummentalhealth.info/2008/04/18/high-anxiety-u-m-research-looks-to-brain-genes-to-improve-treatment/ (2016-05-02)
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  • Building the best brain :: U-M Psychiatry and Depression Center Newsroom
    SIRP alpha grew directly out of previous work on competition between neurons which enables the most active ones to become part of pathways and circuits Read more on this research The team suspected that there must be some sort of signal between the two cells on either side of each synapse something that causes the most active synapses to stabilize So they set out to find out what it was SIRP rise findings The group had previously shown that SIRP alpha was involved in some way in a neuron s ability to form a presynaptic nerve terminal an extension of the cell that reaches out toward a neighboring cell and can send the chemical signals that brain cells use to talk to one another SIRP alpha is also already known to serve an important function in the rest of the body essentially helping normal cells tell the immune system not to attack them It may also help cancer cells evade detection by the immune system s watchdogs In the new study the team studied SIRP alpha function in the brain and started to understand its role in synapse stabilization They focused on the hippocampus a region of the brain very important to learning and memory Through a range of experiments they showed that when a brain cell receives signals from a neighboring cell across a synapse it actually releases SIRP alpha into the space between the cells It does this through the action of molecules inside the cell called CaMK and MMP that act like molecular scissors cutting a SIRP alpha protein in half so that it can float freely away from the cell The part of the SIRP alpha protein that floats into the synapse gap latches on to a receptor on the other side called a CD47 receptor This binding in turn appears to tell the cell that the signal it sent earlier was indeed received and that the synapse is a good one So the cell brings more chemical signaling molecules down that way and releases them into the synapse As more and more nerve messages travel between the sending and receiving cells on either side of that synapse more SIRP alpha gets cleaved released into the synapse and bound to CD47 The researchers believe this repeated process is what helps the cells determine which synapses to keep and which to let wither Umemori says the team next wants to look at what happens when SIRP alpha doesn t get cleaved as it should and at what s happening in cells when a synapse gets eliminated This step of shedding SIRP alpha must be critical to developing a functional neural network he says And if it s not done well disease or disorders may result Perhaps we can use this knowledge to treat diseases caused by defects in synapse formation He notes that the gene for the CD47 receptor is found in the same general area of our DNA as several genes that are suspected to be

    Original URL path: http://ummentalhealth.info/2013/09/24/building-the-best-brain/ (2016-05-02)
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  • Autism social skills curriculum goes global :: U-M Psychiatry and Depression Center Newsroom
    therapists and parents by Dr Yiing Feng Hwang a physician in Tiachung City Taiwan Dr Hwang reported that participants were extremely satisfied and encouraged following the workshop instruction and eager to bring the manual s lessons to life with elementary aged students Since its publication the book has been used across the U S by teachers in a variety of educational settings speech therapists counselors social workers and others leading formal social skills training courses Parents often use individual lessons for skill building with their own children This recent extension of Super Skills is one indication of the curriculum s appeal across cultures who may differ from one another in many ways but whose children with autism share similar struggles in functioning socially The book s lessons are organized under four types of skills necessary for social success fundamental skills social initiation skills getting along with others and social response skills and they are presented in such a way that even inexperienced teachers and other group leaders can follow and implement them successfully A series of practical checklists and other instruments provide a solid foundation for assessing students social skills levels and subsequent program planning Coucouvanis is also the author of The Potty Journey Guide to Toilet Training Children with Special Needs which was a gold medal winner in the 2010 National Parenting Publications Award s NAPPA Parenting Resources Competition Recent Entries Dr Monica Starkman professor emeritus publishes novel based on career in psychiatry Who gets hooked on drugs who stays clean Study in rats finds genetic markers that influence addiction UMHS community mourns death of Kenneth Silk M D Taking the fight against risky pain pill use to the ER Study shows promise Fashion design meets U M research in wearable human stem cell images Featured Video Recent Posts

    Original URL path: http://ummentalhealth.info/2012/10/19/autism-social-skills-curriculum-goes-global/ (2016-05-02)
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  • Greden honored for advancement of depression and bipolar research :: U-M Psychiatry and Depression Center Newsroom
    efforts toward his role as executive director of the Depression Center He is also founder and chair of the National Network of Depression Centers whose membership includes 21 leading depression centers and academic medical centers Focused on advancing research awareness support and advocacy DBSA is the largest patient directed national organization focused on depression and bipolar disorder with a grassroots network of nearly 1 000 patient run support groups across the country The Gerald L Klerman Award is named in honor of the late Klerman M D who was professor and associate chair of research at Cornell University Hospital Medical College Klerman s many research endeavors have had an enormous impact on the understanding of the diagnosis and treatment of mood disorders Recent Entries Dr Monica Starkman professor emeritus publishes novel based on career in psychiatry Who gets hooked on drugs who stays clean Study in rats finds genetic markers that influence addiction UMHS community mourns death of Kenneth Silk M D Taking the fight against risky pain pill use to the ER Study shows promise Fashion design meets U M research in wearable human stem cell images Featured Video Recent Posts Dr Monica Starkman professor emeritus publishes novel based

    Original URL path: http://ummentalhealth.info/2012/04/19/greden-honored-for-advancement-of-depression-and-bipolar-research/ (2016-05-02)
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  • Novick named inaugural Jenkins award recipient :: U-M Psychiatry and Depression Center Newsroom
    by empowering students and faculty to bring original ideas to life Dr Novick s project will identify ways that current technology might allow individuals to better monitor their moods increase their treatment engagement and adherence and also help guide mental health care providers in making more informed and personalized treatment decisions for their patients Read more Recent Entries Dr Monica Starkman professor emeritus publishes novel based on career in psychiatry Who gets hooked on drugs who stays clean Study in rats finds genetic markers that influence addiction UMHS community mourns death of Kenneth Silk M D Taking the fight against risky pain pill use to the ER Study shows promise Fashion design meets U M research in wearable human stem cell images Featured Video Recent Posts Dr Monica Starkman professor emeritus publishes novel based on career in psychiatry Who gets hooked on drugs who stays clean Study in rats finds genetic markers that influence addiction UMHS community mourns death of Kenneth Silk M D Taking the fight against risky pain pill use to the ER Study shows promise Fashion design meets U M research in wearable human stem cell images Twitter Tweets Categories Featured Honors Awards In Memoriam In the

    Original URL path: http://ummentalhealth.info/2012/04/03/novick-named-inaugural-jenkins-award-recipient/ (2016-05-02)
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